abstract：:Behçet's disease is one of the most difficult forms of uveitis to treat. Variety in disease presentation and severity, as well as regional differences in standard of care, demand a tailor-made approach. Anterior segment inflammation generally responds to topical corticosteroids. However, the onset of posterior segment...

journal_title：Ocular immunology and inflammation

authors： Okada AA

更新日期：2000-06-01 00:00:00

abstract：:Human cytomegalovirus (HCMV) is a complex DNA virus encoding more than 200 viral proteins. This highly adapted opportunist agent has developed several ways to evade the immune system. Among all clinical features due to HCMV, retinitis occurs especially in severely immunosuppressed patients, particularly during the end...

journal_title：Ocular immunology and inflammation

authors： Bodaghi B,Michelson S

更新日期：1999-12-01 00:00:00

abstract：:Potent antiretroviral therapy can result in substantial improvement in the immune function of patients with AIDS. In some patients with preexisting cytomegalovirus (CMV) retinitis, a consequence of this improved immune function is increased intraocular inflammation. This phenomenon, termed 'immune recovery uveitis', i...

journal_title：Ocular immunology and inflammation

authors： Holland GN

更新日期：1999-12-01 00:00:00

abstract：:In a South Indian study, an 'in-house' enzyme-linked immunosorbent assay (ELISA) was developed to evaluate the potential of herpes simplex virus (HSV)-specific tear secretory IgA (sIgA) in the diagnosis of herpes simplex keratitis (HSK). The presence of HSV-specific tear sIgA was found to be diagnostic in 20.28% of ca...

journal_title：Ocular immunology and inflammation

authors： Pramod NP,Dhevahi E,Sudhamathi K,Kannan K,Thyagarajan SP

更新日期：1999-06-01 00:00:00

abstract：PURPOSE:Tear lysozyme and tear lactoferrin are enzymes synthesized by the lacrimal gland. Their concentration in human tears reflects tear gland function. Tear gland dysfunction can lead to ocular surface disease. We developed a colorimetric lysozyme assay. The objective of this study was to determine the diagnostic po...

journal_title：Ocular immunology and inflammation

authors： Klaeger AJ,Cevallos V,Sherman MD,Whitcher JP,Stephens RS

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND:Equine uveitis is a spontaneous disorder of horses that can serve as a model for the study of human uveitis. Although the initial presentation is that of an anterior uveitis, retinal involvement has been noted in some cases. We report here the immunohistopathology of retinas from horses with uveitis. METHOD...

journal_title：Ocular immunology and inflammation

authors： Kalsow CM,Dwyer AE

更新日期：1998-12-01 00:00:00

abstract：PURPOSE:Acute posterior multifocal placoid pigment epitheliopathy (APMPPE) is an acquired inflammatory disorder affecting the retina, retinal pigment epithelium, and choroid of healthy adults. APMPPE has been reported to occur after diverse infectious diseases, suggesting a possible immune disorder. The primary site of...

journal_title：Ocular immunology and inflammation

authors： Borruat FX,Piguet B,Herbort CP

更新日期：1998-09-01 00:00:00

abstract：:Tacrolimus (FK506) is effective in Japanese endogenous posterior uveitis (EPU), but there is limited data on its role in refractory EPU where cyclosporin A (CsA) toxicity/resistance develops. This open prospective clinical study aimed to assess the efficacy and adverse effects of low-dose FK506 therapy in western pati...

journal_title：Ocular immunology and inflammation

authors： Kilmartin DJ,Forrester JV,Dick AD

更新日期：1998-06-01 00:00:00

abstract：:The effects of tachykinins on prostaglandin E2 (PGE2)-induced intraocular inflammation were investigated. PGE2 (0.01% or 0.1%) instillation induced iridal hyperemia and protein leakage into the aqueous humor in rabbits, but caused minimal miosis. Intravitreally injected substance P (SP) or neurokinin A (NKA), on the o...

journal_title：Ocular immunology and inflammation

authors： Tsuji F,Hamada M,Shirasawa E

更新日期：1998-03-01 00:00:00

abstract：:Recrudescence is a common and troubling feature of Acanthamoeba keratitis and suggests that corneal infection with this organism fails to stimulate the systemic immune apparatus. The present study examined the cell-mediated and humoral immune responses to Acanthamoeba keratitis in the Chinese hamster. Corneal infectio...

journal_title：Ocular immunology and inflammation

authors： Van Klink F,Leher H,Jager MJ,Alizadeh H,Taylor W,Niederkorn JY

更新日期：1997-12-01 00:00:00

abstract：:Onchocercal keratitis (river blindness) is one of the leading worldwide causes of blindness. Light microscopic analysis of human specimens and corneal tissue from experimental models has implicated the eosinophil as an important cell in the inflammatory response. Our previous studies in experimental murine onchocercal...

journal_title：Ocular immunology and inflammation

authors： Bardenstein DS,Lass JH,Kazura JW,Pearlman E

更新日期：1997-09-01 00:00:00

abstract：AIMS/BACKGROUND:To assess the outcome and complications of cataract extraction in patients with Behçet's disease. METHODS:Thirty-six Behçet's disease patients underwent cataract surgery without intraocular lens implantation. Twenty-six patients had phacoemulsification or extracapsular cataract extraction, and ten pati...

journal_title：Ocular immunology and inflammation

authors： Tabbara KF,Chavis PS

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND:An HLA-DQ1 association has been suspected in patients who develop Propionibacterium acnes endophthalmitis following cataract surgery. New techniques exist which may help to define this association. MATERIALS AND METHODS:Patients with culture-proven P. acnes endophthalmitis following cataract surgery were HL...

journal_title：Ocular immunology and inflammation

authors： Davis JL,Winward KR,Lonardo EC,Nussenblatt RB,Meisler DM,Lee TD

更新日期：1996-01-01 00:00:00

abstract：:Uveitis is an intraocular inflammation that can be caused by infection, autoimmune disease, trauma or malignancy. It is a serious cause of visual handicap and therapy is targeted at: removal of possible infectious agents, the immunological processes that lead to or sustain the inflammation and finally to prevent or tr...

journal_title：Ocular immunology and inflammation

authors： Suttorp-Schulten MS,Jager MJ,Kijlstra A

更新日期：1996-01-01 00:00:00

abstract：:Scleritis is a severe and destructive inflammatory eye disease characterized by extensive extracellular matrix degradation. As in rheumatoid arthritis (RA), tissue destruction in scleritis may be mediated in part by matrix metalloproteinases such as collagenase (MMP-1) and stromelysin (MMP-3) which are normally kept i...

journal_title：Ocular immunology and inflammation

authors： Girolamo ND,McCluskey PJ,Lloyd A,Wakefield D

更新日期：1995-01-01 00:00:00

abstract：:Behçet's disease is the most frequently encountered form of endogenous uveitis in Japan. The authors examined the clinical manifestations in cases with Behçet's disease over six years (1987-1992), and compared the results with those of a previous study (1978-1983). In the more recent study the number of new patients w...

journal_title：Ocular immunology and inflammation

authors： Kotake S,Furudate N,Sasamoto Y,Yoshikawa K,Okamoto T,Goda C,Matsuda H

更新日期：1995-01-01 00:00:00

abstract：:Nedocromil sodium (NS) and sodium cromoglycate (CS) (both applied locally into the conjunctival sac) reduced in a dose dependent manner plasma extravasation induced by topical bradykinin and by topical substance P (SP), NS being approximately ten times more potent than CS. Plasma extravasation induced by SP was unaffe...

journal_title：Ocular immunology and inflammation

authors： Javdan P,Figini M,Ricciardolo FL,Geppetti P

更新日期：1995-01-01 00:00:00

abstract：:Experimental autoimmune uveoretinitis (EAU) induced by immunization of male Lewis rats with bovine S-antigen (S-Ag) is prevented by injection of S-Ag into the testis prior to immunization. This protection of animals is due to the induction of systemic immunotolerance or immunosuppression, which the authors designate o...

journal_title：Ocular immunology and inflammation

authors： Ren J,Singh AK,Shichi H

更新日期：1995-01-01 00:00:00

abstract：:Recent reports have shown that dry eye in Sjögren's syndrome (SS) is associated with reactivation of Epstein-Barr virus (EBV) in lacrimal glands. However, the number of patients examined were few and it has not been determined whether dry eye in the absence of SS is also related to EBV reactivation. The authors exam...

journal_title：Ocular immunology and inflammation

authors： Toda I,Ono M,Fujishima H,Tsubota K

更新日期：1994-01-01 00:00:00

abstract：:The authors investigated 32 human corneal buttons of patients suffering from severe eye burns. The keratoplasties were performed in different periods after the burn and collected within five years. Grafts were followed-up until they failed because of ulceration or until rehabilitating keratoplasties were performed. Ea...

journal_title：Ocular immunology and inflammation

authors： Becker J,Salla S,Redbrake C,Schrage NF,Reim M

更新日期：1994-01-01 00:00:00

abstract：:In the pre-cyclosporin therapy era, BenEzra and Cohen(1) reported an appalling visual prognosis of patients with Behçet's disease, with 74% of eyes losing useful vision six to ten years after diagnosis. This experience was in a population largely of Mediterranean origin and it has been suggested that different ethnic ...

journal_title：Ocular immunology and inflammation

authors： Towler HM,Lightman S

更新日期：1993-01-01 00:00:00

abstract：:The postoperative course of cataract extraction and IOL implantation combined with trabeculectomy in glaucoma patients and of cataract extraction with intraocular lens (IOL) in diabetic patients is more complicated than that of cataract extraction with IOL implantation in otherwise healthy eyes. The main complications...

journal_title：Ocular immunology and inflammation

authors： Zalish M,Rahmiel R,Pollack A,Milstein A,Oliver M

更新日期：1993-01-01 00:00:00

abstract：:The authors present a polymerase chain reaction method for rapid and direct diagnosis of herpetic intraocular infections using small volume samples of intraocular fluid from 29 patients with various intraocular inflammatory diseases and 24 controls with senile cataract. Of six patients with early acute retinal necrosi...

journal_title：Ocular immunology and inflammation

authors： Usui M,Usui N,Goto H,Minoda H,Rai T

更新日期：1993-01-01 00:00:00

abstract：:The surgical technique and immediate results following posterior chamber IOL implantation after cataract extraction in eight children suffering from chronic uveitis are described. In all cases, improvement of the visual acuity and a better control of the intraocular inflammatory processes could be achieved after surge...

journal_title：Ocular immunology and inflammation

authors： Benezra D,Raz J,Cohen E

更新日期：1993-01-01 00:00:00